Clinical Publications

MAESTRO

Agreement, repeatability, and reproducibility of quantitative retinal layer assessment using swept-source and spectral-domain optical coherence tomography in eyes with retinal diseases

AUTHORS:

Hou H, Durbin MK, El-Nimri NW, Fischer JL, Sadda SR*

PUBLICATION:

Front Med. 2023 Dec 18; 10:1281751. doi: 10.3389/fmed.2023.1281751.

Study Purpose

To evaluate the agreement and precision of retinal thickness measurements obtained using swept-source optical coherence tomography (SS-OCT) and spectral-domain OCT (SD-OCT) in healthy eyes and eyes with retinopathy

Overview

Study Design

Prospective

# of Eyes/
Patients

25 normal eyes and 26 eyes with retinal disease, including age-related macular degeneration, macular hole, and diabetic retinopathy

Study Device

3D OCT-1 Maestro
DRI OCT Triton

Outcome Measures

Thickness of the full retina, ganglion cell layer (GCL) + inner plexiform layer (IPL) (GCIPL/abbreviated to GCL+), and ganglion cell complex (GCC/abbreviated to GCL++)

Results

Overall, measurement differences between Triton and Maestro were

IMOvifa reduced measurement time by

39%

FIGURE 1

. Bland–Altman plots show all the average full retinal thickness measurement differences between Maestro and Triton macular cube scans are less than 6 µm in eyes with retinal disease

Conclusions

• The repeatability and reproducibility estimates indicate high precision in both normal and retina groups for full retinal thickness, GCL+, and GCL++ measurements using the Maestro SD-OCT and Triton SS-OCT. • As expected and consistent with other studies, the repeatability and reproducibility in eyes with retinal disease were worse compared with healthy eyes. • This study demonstrated excellent agreement of retinal thickness measurements between the Maestro SD-OCT and Triton SS-OCT.