Clinical Publications

MAESTRO

Comparison of the Thickness of the Fiber Layer of the Retinal Nerves in Spectral Domain Optical Coherence Tomography in Normal Eyes Older Than 40 Years

AUTHORS:

Gündogan M, Kiliç S.

PUBLICATION:

Klin Monbl Augenheilkd. 2021 Sep 15. English. doi: 10.1055/a-1554-5663. Epub ahead of print.

Study Purpose

To compare measurements of the thickness of the retinal nerve fibre layer (RNFL) and assess the agreement between three different devices for spectral domain optical coherence tomography

Overview

Study Design

Prospective, cross-sectional

# of Eyes/
Patients

46 eyes of 23 subjects

Study Device

Topcon Maestro
Canon HS100
NIDEK RS-3000

Outcome Measures

Average RNFL thickness, four quadrants (superior, inferior, nasal, and temporal) of RNFL thickness

Results

The average RNFL thickness measured by the three OCT devices was correlated (p < 0.001), but differed significantly between the three devices
Topcon Maestro showed the highest average RNFL thickness value; the mean average RNFL thickness was 98.5 ± 6.6 µm as measured by Canon HS100, 108.5 ± 8.8 µm as measured by Topcon Maestro, and 104.9 ± 9.0 µm as measured by NIDEK RS-3000
Bland-Altman plots revealed considerable agreement among the three devices, except for the inferior quadrants between Topcon Maestro and NIDEK RS-3000 measurements

IMOvifa reduced measurement time by

39%

Conclusions

Although the peripapillary RNFL thickness measurements taken with Topcon Maestro, Canon HS100, and NIDEK RS-3000 were in good agreement, they were not interchangeable in clinical practice, as the values differed significantly.