Clinical Publications

TRITON

Functional Evaluation of the Visual Pathway in Patients with Multiple Sclerosis Using a Multifunction Stimulator Monitor

AUTHORS:

Satue M, Jarauta L, Obis J, Cipres M, Rodrigo MJ, Almarcegui C, Dolz I, Ara JR, Martin J, Pablo LE, Garcia-Martin E.

PUBLICATION:

Ophthalmol. 2019 Sep 18;2019:2890193. PMID: 31641531 DOI: 10.1155/2019/2890193

Study Purpose

To analyze the correlation between the functional measurements obtained and retinal structural parameters measured with swept source optical coherence tomography (SS-OCT) in patients with multiple sclerosis (MS

Overview

Study Design

Observational, cross-sectional study

# of Eyes/
Patients

• Forty-eight eyes of 48 patients with relapsing-remitting MS (RRMS) and 46 eyes of 46 healthy individuals

Study Device

DRI Triton SS-OCT (Topcon, Tokyo, Japan)
Monpack One (Metrovision, France)

Outcome Measures

• Visual function, GCL in 6 peripapillary sectors, visual acuity (VA), contrast sensitivity vision (CSV), visual field, multifocal PEV and pattern ERG.

Results

Mean age of patients with RRMS and the mean age of controls were 49.25 + 12.98 years and 45.74 + 10.52 years, respectively.
Patients with MS presented reduced low-contrast VA (0.43+0.50 in patients vs. 0.08+0.27 in controls p

IMOvifa reduced measurement time by

39%

Conclusions

• The MS patients presented significant alterations in all visual field parameters compared with healthy controls. • The authors state that this is the first study assessing the correlation between visual function parameters obtained with a multifunction simulator device and SS-OCT technology. • Contrast sensitivity parameters and visual field data correlated most significantly with macular and peripapillary measurements. • More studies are needed to corroborate the findings.