Clinical Publications

TEMPO

Perimetric Comparison Between the IMOvifa™ and Humphrey® Field Analyzer (HFA™)

AUTHORS:

Nishida T, Eslani M, Weinreb RN, Arias J, Vasile C, Mohammadzadeh V, Moghimi S.

PUBLICATION:

J Glaucoma. 2023 Feb 1;32(2):85-92. Epub 2022 Oct 7.

Study Purpose

To evaluate the performance of IMOvifa, a perimeter that performs binocular visual field (VF) testing, and to compare its results with standard automated perimetry

Overview

Study Design

Observational, cross-sectional study

# of Eyes/
Patients

138 eyes of 69 patients, including healthy, glaucoma suspects, and primary open angle glaucoma

Study Device

IMO Smart Visual Function Analyzer (referred to as IMOvifa SVFA)*
Humphrey® Field Analyzer (HFA™)
Melbourne Rapid Fields (MRF)

Outcome Measures

Primary: Mean deviation (MD), pattern standard deviation (PSD), foveal threshold, visual field index (VFI). Secondary: measurement time for visual field

Results

IMOvifa reduced measurement time by 39%
No significant difference in MD (-3.1 dB for HFA vs. -3.1 dB for IMOvifa, P>0.05) or VFI (93.1% for HFA vs. 92.6% for IMOvifa; P>0.05) between HFA 24-2 SITA-Fast and IMOvifa 24-2 AIZE-Rapid
Significant differences were seen in mean PSD (3.2 dB for HFA vs. 4.1 dB for IMOvifa, P0.05 for both), but not for VFI (P=0.031), from pairwise comparisons of AUROC (Figure 2)

IMOvifa reduced measurement time by

39%

FIGURE 1.

Bland-Altman diagram with median difference and agreement limits (including 95% of all difference values). Adapted from J Glaucoma. 2023 Feb 1; 32(2): 85-92. Epub 2022 Oct 7.

FIGURE 2.

Area under the receiver operator characteristic curves for mean deviation (A), pattern SD (B), and visual field index (C). Adapted from J Glaucoma. 2023 Feb 1;32(2):85-92. Epub 2022 Oct 7.

Conclusions

IMOvifa AIZE-Rapid showed good agreement and strong correlation to HFA SITA-Fast for mean deviation, pattern standard deviation, and visual field index. Additionally, IMOvifa shortened visual field test time for healthy and glaucoma patients and reduced fatigue for both patients and examiners.