Clinical Publications

MAESTRO

Robotic Spectral-domain versus Swept-source OCT in the association between OCT-Angiography metrics and glaucoma severity

AUTHORS:

Fazio MA, Clark ME, Girkin CA

PUBLICATION:

Invest. Ophthalmol. Vis. Sci. 2024;65(7):1212.

Study Purpose

To assess the association between OCT-Angiography (OCTA) metrics and glaucoma severity in subjects imaged by a Spectral-domain (SD) robotic OCT and a swept-source (SS) OCT

Overview

Study Design

Prospective, observational

# of Eyes/
Patients

Thirty-four eyes of 26 glaucoma subjects

Study Device

Maestro2 SD-OCT (Topcon Healthcare, Tokyo, Japan) Triton SS-OCT (Topcon Healthcare, Tokyo, Japan) *investigational OCTA acquisition software

Outcome Measures

Linear correlation between radial peripapillary capillary vessel density and visual field mean defect (MD)

Results

Radial peripapillary capillary density showed significant association with VF MD for both robotic SD-OCT (2.067 dB/%, p=0.001655) and SS-OCT (1.94 dB/%, p=0.004026); both associations were independent of layer thickness
Strength of the correlation was higher for the SS-OCT (R2=0.54) than the SD-OCT (R2=0.45) (Figure 1)

IMOvifa reduced measurement time by

39%

FIGURE 1

FIGURE 1.

Linear correlation between radial peripapillary capillary vessel density and visual field mean defect (MD). Scatterplots are color-coded by scan quality’s native score (Q-mean). Adapted from Invest. Ophthalmol. Vis. Sci. 2024;65(7):1212

Conclusions

• Investigational OCTA metrics by Maestro2 (robotic SD-OCT) performed comparably with the Triton’s (SS-OCT) OCTA metrics in their association with glaucoma severity • The highly automated capabilities of the Maestro2’s OCTA may make it a valuable tool for primary eye care and population screening programs