Clinical Publications

MYAH

Suitability of multifunction devices Myah and Myopia Master for monitoring myopia progression in children and adults

AUTHORS:

Chow AHY, Mungalsingh MA, Thai D, Selimos Z, Yan SK, Xu H, Jones DA.

PUBLICATION:

Ophthalmic Physiol Opt. 2024 Jul;44(5):1017-1030. doi: 10.1111/opo.13332. Epub 2024 May 17

Study Purpose

To assess the feasibility of using multifunction instruments to measure axial length for monitoring myopia progression in children and adults

Overview

Study Design

Prospective study

# of Eyes/
Patients

120 right eyes; 60 children (aged 6–18 years) and 60 adults (aged 19–50 years)

Study Device

MYAH (Topcon)
Myopia Master® (Oculus Optikgeräte GmbH)
IOLMaster® 700 (Carl Zeiss Meditec AG)
Lenstar LS900® (Haag-Streit)

Outcome Measures

Repeatability and reproducibility of mean axial length measurement, inter instrument agreement computed as intraclass correlation coefficients, and time taken to obtain a measurement

Results

In children, reproducibility fell within 0.1 mm 95% of the time for the Myah, Myopia Master and IOLMaster 700
Agreement among all devices was classified as excellent (ICC 0.999; 95% CI 0.998–0.999)
The strongest agreement was found between the Myah and the IOLMaster 700, giving the smallest mean difference and narrow limits of agreement (−0.003mm; −0.065 to 0.060)
Measurements for children were significantly faster with the Myah than the IOLMaster 700 (mean difference [SE] −21.90 s [6.01], t117 = −3.65, p = 0.009), Myopia Master (mean difference [SE] −27.14 s [6.659], t117 = −4.52, p < 0.001) and Lenstar LS900 (−85.22 s [6.01], t117 = −14.19, p < 0.001)
In adults, measurement times were similar among the Myah, Myopia Master and IOLMaster 700 (Myah and Myopia Master mean difference [SE] −5.94 s [6.34], t110 = −0.94, p > 0.99; Myah and IOLMaster 700 mean difference [SE] −14.36 s [6.34], t110 = −2.27, p = 0.68; Myopia Master and IOLMaster 700 mean difference [SE] −8.42 s[6.34], t110 = −1.33, p > 0.99)
Measuring adults with the Lenstar LS900 took significantly longer than the Myah, Myopia Master, and the IOL Master 700 (Figure 1)

IMOvifa reduced measurement time by

39%

FIGURE 1

FIGURE 1.

Time to obtain a measurement for all devices split by age group. Significant pairwise comparisons are shown for children only (*p < 0.01; **p < 0.001). Measurements with the Lenstar LS900 took significantly longer than the other three biometers in both children and adults. Adapted from Ophthalmic Physiol Opt. 2024 Jul;44(5):1017-1030

Conclusions

• Myah and Myopia Master multifunction instruments demonstrated good repeatability and reproducibility, and their accuracy was comparable to stand-alone biometers • Axial length measurements using different instruments can be considered interchangeable but should be compared with some caution • The multifunctional instruments Myah and Myopia Master are as well suited for monitoring myopia progression in children as the stand-alone biometers IOLMaster 700 and Lenstar LS900